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Anti-CEACAM1 Antibody (4V352)
还可以产品编号 TMAY-01218
别名 CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP
Anti-CEACAM1 Antibody (4V352) 是一种 Rabbit 抗体，靶向 CEACAM1。Anti-CEACAM1 Antibody (4V352) 可用于 FCM,ICC/IF。
Anti-CEACAM1 Antibody (4V352)
Anti-CEACAM1 Antibody (4V352)
还可以产品编号 TMAY-01218 别名 CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP
Anti-CEACAM1 Antibody (4V352) 是一种 Rabbit 抗体，靶向 CEACAM1。Anti-CEACAM1 Antibody (4V352) 可用于 FCM,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 785 | 5日内发货 | |
| 100 μL | ¥ 2,294 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CEACAM1 Antibody (4V352) is a Rabbit antibody targeting CEACAM1. Anti-CEACAM1 Antibody (4V352) can be used in FCM,ICC/IF. |
| 别名 | CEACAM‑1, CD66a, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), BGPI, BGP1, BGP |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 4V352 |
| 交叉反应 | Human |
| 验证活性 | 1. Flow cytometric analysis of Human CEACAM1(CD66a) expression in HT29 cells. The cells were harvested and stained with purified Rabbit anti-human CEACAM1, then a FITC-conjugated second step antibody. Flow cytometry was performed on a BD™ FACSCalibur flow cytometry system. 2. Immunofluorescence staining of CEACAM1 in HT29 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-human CEACAM1 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). |
| 应用 | FCM,ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM1 / CD66a (rh CEACAM1 / CD66a; TMPY-00717; NP_001020083.1; Met1-Gly428). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/PE |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human CEACAM1 / CD66a protein (TMPY-00717) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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