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Anti-KIF3A Polyclonal Antibody

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货号 TMAB-08046

Anti-KIF3A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KIF3A。Anti-KIF3A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-KIF3A Polyclonal Antibody

Anti-KIF3A Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08046

Anti-KIF3A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KIF3A。Anti-KIF3A Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-KIF3A Polyclonal Antibody is a Rabbit antibody targeting KIF3A. Anti-KIF3A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton (Probable). Cell projection, cilium (By similarity).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The kinesins constitute a large family of microtubule-dependent motor proteins which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell. Individual kinesin members play crucial roles in cell division, intracellular transport and membrane trafficking events including endocytosis and transcytosis. Members of the heterotrimeric kinesin II family of microtubule associated motors generally contain two different motor subunits from the KIF3 family, which includes KIF3A, B and C. KIF3 isoforms mediate anterograde transport of membrane bound organelles in neurons and melanosomes, transport between the endoplasmic reticulum and the Golgi, and transport of protein complexes within cilia and flagella required for their morphogenesis. KIF3A may influence neurogenesis at the level of embryonic cellular events, where the asymmetry of the genetic control circuit controlling left-right (L-R) axis determination is defined. Loss of KIF3A function in mice photoreceptors causes apoptotic cell death, suggesting that kinesin II mediated transport is required for proper cell fate.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KIF3A
抗原种属
Human
基因名称
KIF3A
基因ID
蛋白名称
Kinesin-like protein KIF3A
Uniprot ID
功能
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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