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Anti-GSTP1 Antibody (5M149)

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产品编号 TMAY-00428

Anti-GSTP1 Antibody (5M149) 是一种 Rabbit 抗体,靶向 GSTP1。Anti-GSTP1 Antibody (5M149) 可用于 WB。

Anti-GSTP1 Antibody (5M149)

Anti-GSTP1 Antibody (5M149)

Rating icon 还可以
产品编号 TMAY-00428

Anti-GSTP1 Antibody (5M149) 是一种 Rabbit 抗体,靶向 GSTP1。Anti-GSTP1 Antibody (5M149) 可用于 WB。

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产品介绍

生物活性
产品描述
Anti-GSTP1 Antibody (5M149) is a Rabbit antibody targeting GSTP1. Anti-GSTP1 Antibody (5M149) can be used in WB.
Ig Type
Monoclonal Rabbit IgG
克隆号
5M149
交叉反应
Human
验证活性
1. Anti-GSTP1 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: Jurkat Whole Cell Lysate.

-Lane B: K562 Whole Cell Lysate.

-Lane C: Molt-4 Whole Cell Lysate.

-Lane D: HeLa Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

-Developed using the ECL technique.

-Performed under reducing conditions.

-Predicted band size:23 kDa.

2. Anti-GSTP1 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: Hela Whole Cell Lysate.

-Lane B: GSTP1 konckout Hela Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

-Developed using the ECL technique.

-Performed under reducing conditions.

-Predicted band size:23 kDa.
应用
WB
推荐剂量
WB: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Human GSTP1.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Glutathione S-transferase (GST) family members promote carcinogenesis and cancer progression. GSTP1 levels correlated negatively with tumor size and serum alpha-fetoprotein (AFP) in HCC patients, and higher GSTP1 levels were associated with longer overall survival (OS) and disease-free survival (DFS), the high GSTP1 levels provide a better prognosis through suppression of tumorigenesis in HCC. Dual-testing of HPV and the GSTP1 might prove an effective screening tool for cervical cancer. GSTP1 is highly expressed in various cancerous cells and pre-neoplastic legions, where it is involved in apoptotic resistance or metabolism of several anti-tumor chemotherapeutics. That GSTP1 is a marker of malignant and pre-malignant cells and is a promising target for visualization and drug development. GSTP1 is a largely investigated tissue biomarker in several malignancies such as prostate, breast, lung, and hepatocellular carcinoma with good performances, especially for diagnostic purposes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide corresponding to the N-terminus of the Human GSTP1
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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