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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BDKRB1 Polyclonal Antibody 2

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货号 TMAB-03077

Anti-BDKRB1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 BDKRB1。Anti-BDKRB1 Polyclonal Antibody 2 可用于 WB。

Anti-BDKRB1 Polyclonal Antibody 2

Anti-BDKRB1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-03077

Anti-BDKRB1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 BDKRB1。Anti-BDKRB1 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-BDKRB1 Polyclonal Antibody 2 is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Kinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BDKRB1
抗原种属
Human
基因名称
BDKRB1
基因ID
623
蛋白名称
B1 bradykinin receptor
Uniprot ID
P46663
功能
This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
化学信息
分子量Theoretical: 40 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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