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顶部生物活性储存和溶解信息计算器

Anti-PNPLA2 Polyclonal Antibody

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产品编号 TMAB-01554
别名 TTS2.2, Transport-secretion protein 2 (TTS2), PNPLA2, Pigment epithelium-derived factor receptor (PEDF-R), Patatin-like phospholipase domain-containing protein 2, Desnutrin, Calcium-independent phospholipase A2-zeta (iPLA2-zeta), ATGL, Adipose triglyceride lipase

Anti-PNPLA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PNPLA2。Anti-PNPLA2 Polyclonal Antibody 可用于 FCM,WB。

Anti-PNPLA2 Polyclonal Antibody

Anti-PNPLA2 Polyclonal Antibody

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产品编号 TMAB-01554 别名 TTS2.2, Transport-secretion protein 2 (TTS2), PNPLA2, Pigment epithelium-derived factor receptor (PEDF-R), Patatin-like phospholipase domain-containing protein 2, Desnutrin, Calcium-independent phospholipase A2-zeta (iPLA2-zeta), ATGL, Adipose triglyceride lipase

Anti-PNPLA2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PNPLA2。Anti-PNPLA2 Polyclonal Antibody 可用于 FCM,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PNPLA2 Polyclonal Antibody is a Rabbit antibody targeting PNPLA2. Anti-PNPLA2 Polyclonal Antibody can be used in FCM,WB.
别名TTS2.2, Transport-secretion protein 2 (TTS2), PNPLA2, Pigment epithelium-derived factor receptor (PEDF-R), Patatin-like phospholipase domain-containing protein 2, Desnutrin, Calcium-independent phospholipase A2-zeta (iPLA2-zeta), ATGL, Adipose triglyceride lipase
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat)
验证活性
1. Sample:
Lane 1: Mouse Brown fat tissue lysates
Lane 2: Mouse Heart tissue lysates
Primary: Anti-Adipose Triglyceride Lipase (TMAB-01554) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 52 kDa
2. Blank control: A431. Primary Antibody (green line): Rabbit Anti-Adipose Triglyceride Lipase antibody (TMAB-01554)
Dilution: 3 μg/10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG.
Secondary Antibody: Goat anti-rabbit IgG-AF647
Dilution: 3 μg/test.
Protocol
The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature.
verifiedActivityverifiedActivity
应用FCMWB
推荐剂量
WB: 1:500-2000; FCM: 3ug/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Lipid droplet. Cell membrane.
组织特异性Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner seg
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Adipose triglyceride lipase (ATGL) may function as a lipase and play a role in the adaptive response to a low energy state, such as fasting, by providing fatty acids to other tissues for oxidation. In addition, decreased expression of desnutrin in obesity models suggests its possible contribution to the pathophysiology of obesity. ATGL catalyzes the initial step in triglyceride hydrolysis in mammalian adipose tissue. ATGL contains a patatin domain common to plant acyl hydrolases. ATGL is highly expressed in adipose tissue of mice and humans. It exhibits high substrate specificity for triacylglycerol and is associated with lipid droplets. Inhibition of ATGL markedly decreases total adipose acyl hydrolase activity. Thus, ATGL and HSL coordinately catabolize stored triglycerides in adipose tissue of mammals.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ATGL
抗原种属
Human
基因名称
PNPLA2
基因ID
57104
蛋白名称
Patatin-like phospholipase domain-containing protein 2
Uniprot ID
Q96AD5
研究领域
Lipases,Lipases,Metabolic disorders,Obesity,Lipid metabolism
化学信息
分子量Theoretical: 55 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

TTS2TTS 2.2TTS 2PNPLA 2PEDF-RPEDFRiPLA2-ζiPLA2ζiPLA2-zetaiPLA2zetaCalcium-independent phospholipase A2-ζ (iPLA2-ζ)

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