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Anti-TREML2 Antibody (3V949)
还可以产品编号 TMAY-01964
Anti-TREML2 Antibody (3V949) 是一种 Rabbit 抗体，靶向 TREML2。Anti-TREML2 Antibody (3V949) 可用于 ELISA。
Anti-TREML2 Antibody (3V949)
Anti-TREML2 Antibody (3V949)
还可以产品编号 TMAY-01964
Anti-TREML2 Antibody (3V949) 是一种 Rabbit 抗体，靶向 TREML2。Anti-TREML2 Antibody (3V949) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TREML2 Antibody (3V949) is a Rabbit antibody targeting TREML2. Anti-TREML2 Antibody (3V949) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3V949 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human TREML2 / TLT-2 (rh TREML2 / TLT-2; TMPY-01648; NP_079083.2; Met1-Ser268). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. Murine B7-H3 is specifically bound to Triggering receptor expressed on myeloid cells (TREM)-like transcript 2 (TLT-2, TREML2). TREML2 was expressed on CD8(+) T cells constitutively and on activated CD4(+) T cells. Stimulation with B7-H3 transfectants preferentially up-regulated the proliferation and IFN-gamma production of CD8(+) T cells. Transduction of TREML2 into T cells resulted in enhanced IL-2 and IFN-gamma production via interactions with B7-H3. There may be a direct interaction between B7-H3 and TREML2 that preferentially enhances CD8(+) T cell activation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human TREML2 / TLT-2 protein (TMPY-01648) |
| 抗原种属 | Human |
| 研究领域 | ITIM/ITAM Immunoreceptors and Related Molecules |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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