购物车
- 全部删除
您的购物车当前为空
Anti-PINK1 Polyclonal Antibody
还可以
产品编号 TMAB-01542
别名 Serine/Threonine-Protein Kinase PINK1, Mitochondrial, PTEN-Induced Putative Kinase Protein 1, PTEN Induced Putative Kinase 1, Protein Kinase BRPK, PINK 1, Parkinson Disease(Autosomal Recessive) 6, PARK6, EC 2.7.11.1, BRPK
Anti-PINK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PINK1。Anti-PINK1 Polyclonal Antibody 可用于 WB。
Anti-PINK1 Polyclonal Antibody
Anti-PINK1 Polyclonal Antibody
还可以产品编号 TMAB-01542 别名 Serine/Threonine-Protein Kinase PINK1, Mitochondrial, PTEN-Induced Putative Kinase Protein 1, PTEN Induced Putative Kinase 1, Protein Kinase BRPK, PINK 1, Parkinson Disease(Autosomal Recessive) 6, PARK6, EC 2.7.11.1, BRPK
Anti-PINK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PINK1。Anti-PINK1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-PINK1 Polyclonal Antibody is a Rabbit antibody targeting PINK1. Anti-PINK1 Polyclonal Antibody can be used in WB. |
| 疾病造模方案 | |
| 别名 | Serine/Threonine-Protein Kinase PINK1, Mitochondrial, PTEN-Induced Putative Kinase Protein 1, PTEN Induced Putative Kinase 1, Protein Kinase BRPK, PINK 1, Parkinson Disease(Autosomal Recessive) 6, PARK6, EC 2.7.11.1, BRPK |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Sample: Lane 1: Mouse Muscle tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Heart tissue lysates Lane 4: Rat Muscle tissue lysates Lane 5: Rat Cerebrum tissue lysates Lane 6: Human U-2 OS cell lysates Primary: Anti-PINK1 (TMAB-01542) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64 kDa Observed band size: 58 kDa 2. Sample: Lane 1: Human HeLa cell lysates Lane 2: Human A431 cell lysates Lane 3: Human U-2OS cell lysates Primary: Anti-PINK1 (TMAB-01542) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 64 kDa Observed band size: 60 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Localizes mostly in mitochondrion and the 2 proteolytic processed fragments of 55 kDa and 48 kDa localize mainly in cytosol. |
| 组织特异性 | Highly expressed in heart, skeletal muscle and testis, and at lower levels in brain, placenta, liver, kidney, pancreas, prostate, ovary and small intestine. Present in the embryonic testis from an early stage of development. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human PINK1 |
| 抗原种属 | Human |
| 基因名称 | PINK1 |
| 基因ID | |
| 蛋白名称 | Serine/threonine-protein kinase PINK1, mitochondrial |
| Uniprot ID | |
| 研究领域 | Cardiac metabolism,Mitochondrial markers,Mitophagy fission and fusion,Neurodegenerative disease,Parkinson's disease,Mitochondrial,Other Kinases |
| 功能 | Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PRKN . Targets PRKN to dysfunctional depolarized mitochondria through the phosphorylation of MFN2 . Activates PRKN in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PRKN and (2) mediating phosphorylation of ubiquitin, converting PRKN to its fully-active form . Required for ubiquinone reduction by mitochondrial complex I by mediating phosphorylation of complex I subunit NDUFA10 (By similarity). |
| 分子量 | Theoretical: 64 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
评论列表
预览
Related Tags: buy Anti-PINK1 Polyclonal Antibody | purchase Anti-PINK1 Polyclonal Antibody | Anti-PINK1 Polyclonal Antibody cost | order Anti-PINK1 Polyclonal Antibody | Anti-PINK1 Polyclonal Antibody molecular weight
嗨！有任何问题？点我咨询
评论内容