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Anti-IL2RA/CD25 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL2RA/CD25。Anti-IL2RA/CD25 Polyclonal Antibody 可用于 WB,FCM。
Anti-IL2RA/CD25 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL2RA/CD25。Anti-IL2RA/CD25 Polyclonal Antibody 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-IL2RA/CD25 Polyclonal Antibody is a Rabbit antibody targeting IL2RA/CD25. Anti-IL2RA/CD25 Polyclonal Antibody can be used in WB,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 0.2ug /test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] |
| 免疫原 | KLH conjugated synthetic peptide: mouse CD25 |
| 抗原种属 | Mouse |
| 基因名称 | IL2RA |
| 基因ID | |
| 蛋白名称 | Interleukin-2 receptor subunit alpha |
| Uniprot ID | |
| 功能 | Receptor for interleukin-2. |
| 分子量 | Theoretical: 28 kDa. Actual: 55 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |