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Anti-Oligophrenin 1 Polyclonal Antibody 2

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货号 TMAB-09770

Anti-Oligophrenin 1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Oligophrenin 1。Anti-Oligophrenin 1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Oligophrenin 1 Polyclonal Antibody 2

Anti-Oligophrenin 1 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-09770

Anti-Oligophrenin 1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Oligophrenin 1。Anti-Oligophrenin 1 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Oligophrenin 1 Polyclonal Antibody 2 is a Rabbit antibody targeting Oligophrenin 1. Anti-Oligophrenin 1 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, synapse. Cell projection, axon. Cell projection, dendritic spine. Note=Present in both presynaptic and postsynaptic sites
组织特异性Expressed in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景Ras p21 can exist in either a physiologically quiescent GDP-binding state or a GTP-binding signal-emitting state (1,2). Interaction of Ras p21 with GTPase activating protein (GAP) can increase the rate of hydrolysis of Ras p21-bound GTP by as much as 1000-fold (3). In mitogenically activated and tyrosine kinase-transformed cells, Ras GAP forms a complex with a protein designated p190 (4). At its amino terminus, p190 contains sequence motifs characteristic of all known GTPases, whereas the carboxy terminus contains sequences similar to those found in the Bcr gene product, n-chimerin and Rho GAP, all of which exhibit intrinsic GAP activity (4,5). Oligophrenein-1 is an additional protein with GTPase activating activity. Oligophrenein-1 is a RhoGAP protein that stimulates GTP hydrolysis of Rho subfamily members and is involved in cell migration, morphogenesis and axon outgrowth (6).
抗原信息
免疫原
KLH conjugated synthetic peptide: human Oligophrenin 1
抗原种属
Human
基因名称
OPHN1
基因ID
4983
蛋白名称
Oligophrenin-1
Uniprot ID
O60890
功能
Stimulates GTP hydrolysis of members of the Rho family. Could activates GTPase targets that are known to affect cell migration and outgrowth of axons and dendrites.
化学信息
分子量Theoretical: 92 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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