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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DEDD1 Polyclonal Antibody

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货号 TMAB-05054

Anti-DEDD1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DEDD1。Anti-DEDD1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-DEDD1 Polyclonal Antibody

Anti-DEDD1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05054

Anti-DEDD1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DEDD1。Anti-DEDD1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-DEDD1 Polyclonal Antibody is a Rabbit antibody targeting DEDD1. Anti-DEDD1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Pig,Cow)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus, nucleolus.
组织特异性Widely expressed with highest levels in testis.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DEDD1
抗原种属
Human
基因名称
DEDD
基因ID
9191
蛋白名称
Death effector domain-containing protein
Uniprot ID
O75618
功能
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro.
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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