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Anti-FOLR2 Polyclonal Antibody

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货号 TMAB-00696

别名 β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR

Anti-FOLR2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FOLR2。Anti-FOLR2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-FOLR2 Polyclonal Antibody

Anti-FOLR2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-00696 别名 β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR

Anti-FOLR2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 FOLR2。Anti-FOLR2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-FOLR2 Polyclonal Antibody is a Rabbit antibody targeting FOLR2. Anti-FOLR2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
别名β-HFR, FR-β, FR-P3, FR-BETA, folate receptor 2 (fetal), FBP/PL-1, FBP, BETA-HFR
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Horse)
验证活性
1. Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-FOLR2 Polyclonal Antibody, Unconjugated (TMAB-00696) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Sample:
Lane 1: Recombinant human FOLR2 protein, N-His
Primary: Anti-FOLR2 (TMAB-00696) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25 kDa
Observed band size: 25 kDa
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Secreted.
组织特异性Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Folate receptor
抗原种属
Human
基因名称
FOLR2
基因ID
蛋白名称
Folate receptor beta
Uniprot ID
研究领域
Vitamins / minerals,Vitamins / Minerals
功能
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.
化学信息
分子量Theoretical: 25 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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