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Anti-PEDF Antibody (9F493)

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产品编号 TMAY-03840

Anti-PEDF Antibody (9F493) 是一种 Rabbit 抗体,靶向 PEDF。Anti-PEDF Antibody (9F493) 可用于 ELISA。

Anti-PEDF Antibody (9F493)

Anti-PEDF Antibody (9F493)

Rating icon 还可以
产品编号 TMAY-03840

Anti-PEDF Antibody (9F493) 是一种 Rabbit 抗体,靶向 PEDF。Anti-PEDF Antibody (9F493) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
9F493
交叉反应
Rat
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat SerpinF1/PEDF (rR SerpinF1/PEDF; TMPY-00266; NP_808788.1; Met1-Thr418).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Rat SerpinF1/PEDF Protein (TMPY-00266)
抗原种属
Rat
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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