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Anti-PEDF Antibody (9F493) 是一种 Rabbit 抗体,靶向 PEDF。Anti-PEDF Antibody (9F493) 可用于 ELISA。
Anti-PEDF Antibody (9F493) 是一种 Rabbit 抗体,靶向 PEDF。Anti-PEDF Antibody (9F493) 可用于 ELISA。
产品描述 | Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9F493 |
交叉反应 | Rat |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Rat SerpinF1/PEDF (rR SerpinF1/PEDF; TMPY-00266; NP_808788.1; Met1-Thr418). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression. |
偶联 | Unconjugated |
免疫原 | Recombinant Rat SerpinF1/PEDF Protein (TMPY-00266) |
抗原种属 | Rat |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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