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Anti-CHGA Antibody (9D68)

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Anti-CHGA Antibody (9D68)
产品编号 TMAC-00855

Anti-CHGA Antibody (9D68) 是一种 Rabbit 抗体,靶向 CHGA。Anti-CHGA Antibody (9D68) 可用于 WB,ICC/IF,IHC。

Anti-CHGA Antibody (9D68)

Anti-CHGA Antibody (9D68)

Rating icon 还可以
Anti-CHGA Antibody (9D68)
产品编号 TMAC-00855

Anti-CHGA Antibody (9D68) 是一种 Rabbit 抗体,靶向 CHGA。Anti-CHGA Antibody (9D68) 可用于 WB,ICC/IF,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-CHGA Antibody (9D68) is a Rabbit antibody targeting CHGA. Anti-CHGA Antibody (9D68) can be used in WB,ICC/IF,IHC.
Ig Type
IgG
克隆号
9D68
交叉反应
Human
验证活性
1. Western blot analysis of Chromogranin A on PC-12 cells lysates using anti-Chromogranin A antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Chromogranin A antibody. Counter stained with hematoxylin.
3. ICC staining Chromogranin A in PC-3M cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine, neuroendocrine and neuronal tissue. Family members include chromogranin A (Chr-A), chromogranin B (Chr-B, also known as secretogranin I) chromogranin C (also known as secretogranin II or Sg II), secretogranin III (Sg III or SCG3). High levels of Chr-A expression is a characteristic of neuroendocrine tumors. Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, exocrine pancreatic secretion and gastric acid secretion. Pancreastatin exists as two forms; the major form is expressed in stomach and colon extracts. In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, while levels of Chr-A and Chr-B showed little or no increase. Sg III is an acidic secretory protein expressed in neuronal and endocrine cells. In the anterior lobe of the rat pituitary gland, Sg III is present in mammotropes and thyrotropes, moderately in gonadotropes and corticotropes, though not in somatotropes. Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 86 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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