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Anti-Phospho-Tau (Thr217) Antibody (1W171)
还可以产品编号 TMAY-01632
Anti-Phospho-Tau (Thr217) Antibody (1W171) 是一种 Rabbit 抗体，靶向 Phospho-Tau (Thr217)。Anti-Phospho-Tau (Thr217) Antibody (1W171) 可用于 WB。
Anti-Phospho-Tau (Thr217) Antibody (1W171)
Anti-Phospho-Tau (Thr217) Antibody (1W171)
还可以产品编号 TMAY-01632
Anti-Phospho-Tau (Thr217) Antibody (1W171) 是一种 Rabbit 抗体，靶向 Phospho-Tau (Thr217)。Anti-Phospho-Tau (Thr217) Antibody (1W171) 可用于 WB。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-Tau (Thr217) Antibody (1W171) is a Rabbit antibody targeting Phospho-Tau (Thr217). Anti-Phospho-Tau (Thr217) Antibody (1W171) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1W171 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of extracts from mouse brain, untreated (line A); treated with λ-phosphatase (line B) using Phospho-Tau (Thr217) rabbit monoclonal Antibody at 1:2000 dilution. (Validation Experiment) 2. Western blot analysis of extracts from Hela using Phospho-Tau (Thr217) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment) 3. Western blot analysis of extracts from Rat brain using Phospho-Tau (Thr217) rabbit monoclonal Antibody at 1:10000 dilution. 4. Western blot analysis of 200 ng Recombinant Human Tau Protein (Full Length) (line A) and 200 ng Recombinant Human Tau Protein (Full Length), GSK3beta-phosphorylated (line B) using Phospho-Tau (Thr217) Rabbit Monoclonal Antibody at 1:5000 dilution. |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-1:5000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the residues around Thr217 of Human Phospho-Tau |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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