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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody

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货号 TMAB-11188

Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PSD93 (Tyr340)。Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody 可用于 WB。

Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody

Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11188

Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-PSD93 (Tyr340)。Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PSD93 (Tyr340). Anti-Phospho-PSD93 (Tyr340) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Lipid-anchor. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note=Concentrated in soma and postsynaptic density of a subset of neurons.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human PSD93 around the phosphorylation site of Tyr340
抗原种属
Human
基因名称
DLG2
基因ID
1740
蛋白名称
Disks large homolog 2
Uniprot ID
Q15700
功能
Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
化学信息
分子量Theoretical: 98 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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