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Anti-Phospho-BLK (Tyr501) Polyclonal Antibody

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Anti-Phospho-BLK (Tyr501) Polyclonal Antibody
产品编号 TMAC-00446
别名 p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)

Anti-Phospho-BLK (Tyr501) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BLK (Tyr501)。Anti-Phospho-BLK (Tyr501) Polyclonal Antibody 可用于 IHC。

Anti-Phospho-BLK (Tyr501) Polyclonal Antibody

Anti-Phospho-BLK (Tyr501) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody
产品编号 TMAC-00446 别名 p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)

Anti-Phospho-BLK (Tyr501) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-BLK (Tyr501)。Anti-Phospho-BLK (Tyr501) Polyclonal Antibody 可用于 IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-BLK (Tyr501) Polyclonal Antibody is a Rabbit antibody targeting Phospho-BLK (Tyr501). Anti-Phospho-BLK (Tyr501) Polyclonal Antibody can be used in IHC.
别名p-BLK (Y501), p-BLK (Tyr501), BLK (p-Y501), BLK (p-Tyr501)
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BLK (Phospho-Tyr501) antibody TMAC-00446 (left)or the same antibody preincubated with blocking peptide (right).
应用
推荐剂量
IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Non-receptor tyrosine kinase involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulins and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 501 (R-Q-Y(p)-E-L) derived from Human BLK
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 57 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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