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Anti-Fbx32 Antibody (6J554)
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产品编号 TMAC-01450
别名 Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, FBX32, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik
Anti-Fbx32 Antibody (6J554) 是一种 Rabbit 抗体，靶向 Fbx32。Anti-Fbx32 Antibody (6J554) 可用于 WB,ICC。
Anti-Fbx32 Antibody (6J554)
Anti-Fbx32 Antibody (6J554)
还可以产品编号 TMAC-01450 别名 Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, FBX32, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik
Anti-Fbx32 Antibody (6J554) 是一种 Rabbit 抗体，靶向 Fbx32。Anti-Fbx32 Antibody (6J554) 可用于 WB,ICC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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抗原信息
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| 产品描述 | Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in WB,ICC. |
| 别名 | Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, FBX32, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Fbx32 on mouse skeletal muscle tissue using anti-Fbx32 antibody at 1/1,000 dilution. 2. ICC staining Fbx32 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining Fbx32 in L6 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; ICC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: human Fbx32 1-200aa |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 41 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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