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Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PRKDC (Thr2609)。Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody 可用于 WB。
Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-PRKDC (Thr2609)。Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PRKDC (Thr2609). Anti-Phospho-PRKDC (Thr2609) Polyclonal Antibody can be used in WB. |
别名 | XRCC7, XRCC 7, Protein Kinase DNA Activated Catalytic Polypeptide, PRKDC (p-Thr2609), PRKDC (p-T2609), PRKDC, p-PRKDC (Thr2609), p-PRKDC (T2609), PKRDC, Phospho-PRKDC (T2609), p460, p350, IMD26, HYRC1, HYRC 1, HYRC, Hyperradiosensitivity complementing 1, Hyper radiosensitivity of murine scid mutation, DNPK1, DNPK 1, DNA-PKcs, DNAPK catalytic subunit, DNAPK, DNA PK catalytic subunit, DNA dependent protein kinase catalytic subunit, complementing 1 |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of extracts from K562 cells untreated (lane 1) or treated with hydroxyurea (lane 2) using DNA PKcs (Phospho-Thr2609) antibody TMAC-01157. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 2609 (V-E-T(p)-Q-A) derived from Human DNA-PK |
抗原种属 | human |
Uniprot ID |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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