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LAMP3/CD208 Protein, Human, Recombinant (His)

LAMP3/CD208 Protein, Human, Recombinant (His)

产品编号 TMPY-01013
别名: LAMP, DC LAMP, lysosomal associated membrane protein 3, DCLAMP, CD208, TSC403, LAMP-3, DC-LAMP

LAMP3/CD208 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is Q9UQV4.

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LAMP3/CD208 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
100 μg ¥ 4,460 5日内发货
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产品目录号及名称: LAMP3/CD208 Protein, Human, Recombinant (His) (TMPY-01013)
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生物活性 Testing in progress
产品描述 LAMP3/CD208 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is Q9UQV4.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 Q9UQV4
别名 LAMP, DC LAMP, lysosomal associated membrane protein 3, DCLAMP, CD208, TSC403, LAMP-3, DC-LAMP
蛋白构建 mature form of Human LAMP3 (NP_055213.2) (Lys 28-Thr 381) with a carboxy-terminal polyhistidine tag
蛋白纯度 > 95 % as determined by SDS-PAGE
分子量 39 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces.

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Keywords

LAMP3/CD208 Protein, Human, Recombinant (His) LAMP CD-208 LAMP3 DC LAMP lysosomal associated membrane protein 3 DCLAMP CD208 TSC403 TSC 403 LAMP 3 LAMP-3 TSC-403 CD 208 DC-LAMP recombinant recombinant-proteins proteins protein

 

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