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Anti-PDGF-D/SCDGFB Polyclonal Antibody 2

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货号 TMAB-10122

Anti-PDGF-D/SCDGFB Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PDGF-D/SCDGFB。Anti-PDGF-D/SCDGFB Polyclonal Antibody 2 可用于 WB。

Anti-PDGF-D/SCDGFB Polyclonal Antibody 2

Anti-PDGF-D/SCDGFB Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-10122

Anti-PDGF-D/SCDGFB Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 PDGF-D/SCDGFB。Anti-PDGF-D/SCDGFB Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-PDGF-D/SCDGFB Polyclonal Antibody 2 is a Rabbit antibody targeting PDGF-D/SCDGFB. Anti-PDGF-D/SCDGFB Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted. Note=Released by platelets upon wounding.
组织特异性Expressed at high levels in the heart, pancreas, adrenal gland and ovary and at low levels in placenta, liver, kidney, prostate, testis, small intestine, spleen and colon. In the kidney, expressed by the visceral epithelial cells of the glomeruli. A widespread expression is also seen in the medial smooth muscle cells of arteries and arterioles, as well as in smooth muscle cells of vasa rectae in the medullary area. Expressed in the adventitial connective tissue surrounding the suprarenal artery. In chronic obstructive nephropathy, a persistent expression is seen in glomerular visceral epithelial cells and vascular smooth muscle cells, as well as de novo expression by periglomerular interstitial cells and by some neointimal cells of atherosclerotic vessels. Expression in normal prostate is seen preferentially in the mesenchyme of the gland while expression is increased and more profuse in prostate carcinoma. Expressed in many ovarian, lung, renal and brain cancer-derived cell lines.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SCDGFB (Spinal cord derived growth factor B) is a member of the platelet derived growth factor family. It only forms homodimers and does not dimerize with the other three family members. It is a potent mitogen for cells of mesenchymal origin. It is activated by proteolytic cleavage and this active form acts as a specific ligand for beta platelet derived growth factor receptor. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. It induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PDGF-D/SCDGFB
抗原种属
Human
基因名称
PDGFD
基因ID
80310
蛋白名称
Platelet-derived growth factor D
Uniprot ID
Q9GZP0
功能
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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