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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BMP-4 Polyclonal Antibody

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货号 TMAB-00243

别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BMP-4。Anti-BMP-4 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-BMP-4 Polyclonal Antibody

Anti-BMP-4 Polyclonal Antibody

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货号 TMAB-00243 别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BMP-4。Anti-BMP-4 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-BMP-4 Polyclonal Antibody is a Rabbit antibody targeting BMP-4. Anti-BMP-4 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
别名ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Ig Type
IgG
反应种属
Mouse,Sheep (predicted:Human,Rat)
验证活性
1. Sample:
Sheep skin (Sheep) Lysate at 40 μg
Primary: Anti-BMP4 (TMAB-00243) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 13/45 kDa
Observed band size: 50 kDa
2. Paraformaldehyde-fixed, paraffin embedded (mouse pancreas tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (BMP4) Polyclonal Antibody, Unconjugated (TMAB-00243) at 1:400 overnight at 4°C, followed by a conjugated secondary for 20 min and DAB staining.
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BMP4
抗原种属
Human
基因名称
BMP4
基因ID
652
蛋白名称
Bone morphogenetic protein 4
Uniprot ID
P12644
研究领域
TGF,TGF,Kidney development,Gut specification,Nervous system development,TGF,Secreted
功能
Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.
化学信息
分子量Theoretical: 13/45 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

OFC-11OFC 11MCOPS-6MCOPS 6
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