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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-BAMBI Polyclonal Antibody

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货号 TMAB-00184

别名 BMP and activin membrane-bound inhibitor, 2610003H06Rik

Anti-BAMBI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BAMBI。Anti-BAMBI Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

Anti-BAMBI Polyclonal Antibody

Anti-BAMBI Polyclonal Antibody

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货号 TMAB-00184 别名 BMP and activin membrane-bound inhibitor, 2610003H06Rik

Anti-BAMBI Polyclonal Antibody 是一种 Rabbit 抗体，靶向 BAMBI。Anti-BAMBI Polyclonal Antibody 可用于 IF,IHC-Fr,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-BAMBI Polyclonal Antibody is a Rabbit antibody targeting BAMBI. Anti-BAMBI Polyclonal Antibody can be used in IF,IHC-Fr,WB.
别名BMP and activin membrane-bound inhibitor, 2610003H06Rik
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Pig,Cow,Rabbit,Sheep,GuineaPig)
验证活性
1. Sample:
Testis (Mouse) Lysate at 40 μg
Spleen (Mouse) Lysate at 40 μg
Primary: Anti-BAMBI (TMAB-00184) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kDa
Observed band size: 30 kDa
2. Sample:
Lane 1: K562 (Human) Cell Lysate at 30 μg
Lane 2: MCF-7 (Human) Cell Lysate at 30 μg
Lane 3: HepG2 (Human) Cell Lysate at 30 μg
Lane 4: A549 (Human) Cell Lysate at 30 μg
Primary:
Anti-BAMBI (TMAB-00184) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 29 kDa
Observed band size: 30 kDa
3. Sample:
RAW264.7 (Mouse) CellLysate at 30 μg
Primary: Anti-BAMBI (TMAB-00184) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kDa
Observed band size: 30 kDa
verifiedActivityverifiedActivityverifiedActivity
应用IFIHC-FrWB
推荐剂量
WB: 1:500-2000; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-β signaling during development. The BAMBI family of proteins are related to type I TGF-β receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of β-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
抗原信息
免疫原
KLH conjugated synthetic peptide: human BAMBI
抗原种属
Human
基因名称
BAMBI
基因ID
25805
蛋白名称
BMP and activin membrane-bound inhibitor homolog
Uniprot ID
Q13145
研究领域
TGF,Surface Molecules
功能
Negatively regulates TGF-beta signaling.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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