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Thioredoxin/TRX Protein, Mouse, Recombinant

Thioredoxin/TRX Protein, Mouse, Recombinant

产品编号 TMPY-00382
别名: Txn, Txn1, thioredoxin

Thioredoxin/TRX Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10639.

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Thioredoxin/TRX Protein, Mouse, Recombinant
规格 价格/CNY 货期 数量
100 μg ¥ 3,820 现货
200 μg ¥ 6,530 5日内发货
500 μg ¥ 13,220 5日内发货
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产品目录号及名称: Thioredoxin/TRX Protein, Mouse, Recombinant (TMPY-00382)
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生物活性 Measured by its ability to catalyze the reduction of insulin. The reaction leads to precipitation, which can be measured by absorbance at 650 nm. The specific activity is >4 A650/min/mg.
产品描述 Thioredoxin/TRX Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.7 kDa and the accession number is P10639.
种属 Mouse
表达系统 E. coli
标签 Tag Free
蛋白编号 P10639
别名 Txn, Txn1, thioredoxin
蛋白构建 The Mouse Txn (P10639) (Met1-Val105) was expressed and purified.
蛋白纯度 > 95 % as determined by SDS-PAGE

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分子量 11.7 kDa (predicted)
内毒素 Please contact us for more information.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. Thioredoxins are found in nearly all known organisms and are essential for life in mammals. Thioredoxin / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Thioredoxin / TXN plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Thioredoxin / TXN nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Thioredoxin / TXN induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

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Keywords

Thioredoxin/TRX Protein, Mouse, Recombinant Txn Txn1 thioredoxin recombinant recombinant-proteins proteins protein

 

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