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Anti-CD144/VE Cadherin Antibody (9I480)

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货号 TMAB-03851

Anti-CD144/VE Cadherin Antibody (9I480) 是一种 Rabbit 抗体,靶向 CD144/VE Cadherin。Anti-CD144/VE Cadherin Antibody (9I480) 可用于 WB,ICC/IF,IP。

Anti-CD144/VE Cadherin Antibody (9I480)

Anti-CD144/VE Cadherin Antibody (9I480)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03851

Anti-CD144/VE Cadherin Antibody (9I480) 是一种 Rabbit 抗体,靶向 CD144/VE Cadherin。Anti-CD144/VE Cadherin Antibody (9I480) 可用于 WB,ICC/IF,IP。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍


生物活性
产品描述
Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP.
Ig Type
IgG
克隆号
9I480
反应种属
Mouse
应用WBICC/IFIP
推荐剂量
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries.
组织特异性Endothelial tissues and brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
抗原信息
免疫原
A synthesized peptide: mouse Cadherin 5
抗原种属
Mouse
基因名称
CDH5
基因ID
蛋白名称
Cadherin-5
Uniprot ID
功能
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
化学信息
分子量Theoretical: 88 kDa. Actual: 90, 125 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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