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Anti-CD144/VE Cadherin Antibody (9I480) 是一种 Rabbit 抗体,靶向 CD144/VE Cadherin。Anti-CD144/VE Cadherin Antibody (9I480) 可用于 WB,ICC/IF,IP。
Anti-CD144/VE Cadherin Antibody (9I480) 是一种 Rabbit 抗体,靶向 CD144/VE Cadherin。Anti-CD144/VE Cadherin Antibody (9I480) 可用于 WB,ICC/IF,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 790 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-CD144/VE Cadherin Antibody (9I480) is a Rabbit antibody targeting CD144/VE Cadherin. Anti-CD144/VE Cadherin Antibody (9I480) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| 克隆号 | 9I480 |
| 反应种属 | Mouse |
| 应用 | WBICC/IFIP |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries. |
| 组织特异性 | Endothelial tissues and brain. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. |
| 免疫原 | A synthesized peptide: mouse Cadherin 5 |
| 抗原种属 | Mouse |
| 基因名称 | CDH5 |
| 基因ID | |
| 蛋白名称 | Cadherin-5 |
| Uniprot ID | |
| 功能 | Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. |
| 分子量 | Theoretical: 88 kDa. Actual: 90, 125 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |