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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Fbx15 Polyclonal Antibody

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货号 TMAB-05915

Anti-Fbx15 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Fbx15。Anti-Fbx15 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Fbx15 Polyclonal Antibody

Anti-Fbx15 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05915

Anti-Fbx15 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Fbx15。Anti-Fbx15 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Fbx15 Polyclonal Antibody is a Rabbit antibody targeting Fbx15. Anti-Fbx15 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit. Cytoplasm. Note=Expressed in clathrin-coated pits, a soluble form is possibly derived by cleavage at the cell surface.
组织特异性Epithelial cells of kidney glomerulus and proximal tubule, lung, epididymis, yolk sac, among others.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Fbx15
抗原种属
Human
基因名称
FBXO15
基因ID
201456
蛋白名称
F-box only protein 15
Uniprot ID
Q8NCQ5
功能
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity).
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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