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Anti-CD8 alpha Antibody (2E357) 是一种 Rabbit 抗体,靶向 CD8 alpha。Anti-CD8 alpha Antibody (2E357) 可用于 ELISA。
Anti-CD8 alpha Antibody (2E357) 是一种 Rabbit 抗体,靶向 CD8 alpha。Anti-CD8 alpha Antibody (2E357) 可用于 ELISA。
产品描述 | Anti-CD8 alpha Antibody (2E357) is a Rabbit antibody targeting CD8 alpha. Anti-CD8 alpha Antibody (2E357) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 2E357 |
交叉反应 | Ferret |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Ferret CD8a (rF CD8a; TMPY-02165; ABS50091.1; Met1-Glu186). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections. |
偶联 | Unconjugated |
免疫原 | Recombinant Ferret CD8a protein (TMPY-02165) |
抗原种属 | Ferret |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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