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Anti-Erythropoietin Antibody (3V254)

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产品编号 TMAY-03548

Anti-Erythropoietin Antibody (3V254) 是一种 Rabbit 抗体,靶向 Erythropoietin。Anti-Erythropoietin Antibody (3V254) 可用于 IHC-P。

Anti-Erythropoietin Antibody (3V254)

Anti-Erythropoietin Antibody (3V254)

Rating icon 还可以
产品编号 TMAY-03548

Anti-Erythropoietin Antibody (3V254) 是一种 Rabbit 抗体,靶向 Erythropoietin。Anti-Erythropoietin Antibody (3V254) 可用于 IHC-P。

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产品介绍

生物活性
产品描述
Anti-Erythropoietin Antibody (3V254) is a Rabbit antibody targeting Erythropoietin. Anti-Erythropoietin Antibody (3V254) can be used in IHC-P.
Ig Type
Monoclonal Rabbit IgG
克隆号
3V254
交叉反应
Mouse
验证活性
1. Immunochemical staining of Mouse Erythropoietin in Mouse kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.

2. Immunochemical staining of Mouse Erythropoietin in Mouse liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
应用
IHC-P
推荐剂量
IHC-P: 1:50-1:200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Erythropoietin (rM Erythropoietin; TMPY-00443; NP_031968.1; Met1-Arg192).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. It also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. Genetic variation in erythropoietin is associated with susceptbility to microvascular complications of diabetes type 2. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis. It has a longer circulating half-life in vivo. Erythropoietin is being much misused as a performance-enhancing drug in endurance athletes.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse Erythropoietin Protein (TMPY-00443)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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