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Anti-TREM-2 Polyclonal Antibody

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货号 TMAB-01893

别名 triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2

Anti-TREM-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TREM-2。Anti-TREM-2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-TREM-2 Polyclonal Antibody

Anti-TREM-2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01893 别名 triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2

Anti-TREM-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TREM-2。Anti-TREM-2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
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产品介绍


生物活性
产品描述
Anti-TREM-2 Polyclonal Antibody is a Rabbit antibody targeting TREM-2. Anti-TREM-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
别名triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
1. Sample:
Lane 1: Mouse Raw264.7 cell lysates
Lane 2: Mouse Spleen tissue lysates
Lane 3: Mouse Cerebrum tissue lysates
Lane 4: Mouse BV2 cell lysates
Lane 5: Mouse Lung tissue lysates
Lane 6: Rat Spleen tissue lysates
Lane 7: Rat Cerebrum tissue lysates
Primary: Anti-TREM2 (TMAB-01893) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 25 kDa
Observed band size: 24 kDa
2. Paraformaldehyde-fixed, paraffin embedded Human Glioma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TREM2 Polyclonal Antibody, Unconjugated (TMAB-01893) at 1:150 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Isoform 2: Secreted (Potential).Isoform 3: Secreted (Potential).
组织特异性Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]
抗原信息
免疫原
KLH conjugated synthetic peptide: human TREM2
抗原种属
Human
基因名称
TREM2
基因ID
蛋白名称
Triggering receptor expressed on myeloid cells 2
Uniprot ID
研究领域
Macrophage / Inflamm.
功能
May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
化学信息
分子量Theoretical: 25 kDa. Actual: 35-40 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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