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别名 triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2
Anti-TREM-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TREM-2。Anti-TREM-2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。
Anti-TREM-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TREM-2。Anti-TREM-2 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 |
| 产品描述 | Anti-TREM-2 Polyclonal Antibody is a Rabbit antibody targeting TREM-2. Anti-TREM-2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| 别名 | triggering receptor expressed on myeloid cells 2, Trem2c, Trem2b, Trem2a, TREM-2 |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat |
| 验证活性 | 1. Sample: Lane 1: Mouse Raw264.7 cell lysates Lane 2: Mouse Spleen tissue lysates Lane 3: Mouse Cerebrum tissue lysates Lane 4: Mouse BV2 cell lysates Lane 5: Mouse Lung tissue lysates Lane 6: Rat Spleen tissue lysates Lane 7: Rat Cerebrum tissue lysates Primary: Anti-TREM2 (TMAB-01893) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25 kDa Observed band size: 24 kDa 2. Paraformaldehyde-fixed, paraffin embedded Human Glioma; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TREM2 Polyclonal Antibody, Unconjugated (TMAB-01893) at 1:150 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. ![]() ![]() |
| 应用 | IFIHC-FrIHC-PWB |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential). Isoform 2: Secreted (Potential).Isoform 3: Secreted (Potential). |
| 组织特异性 | Expressed on macrophages and dendritic cells but not on granulocytes or monocytes. In the CNS strongest expression seen in the basal ganglia, corpus callosum, medulla oblongata and spinal cord. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
| 免疫原 | KLH conjugated synthetic peptide: human TREM2 |
| 抗原种属 | Human |
| 基因名称 | TREM2 |
| 基因ID | |
| 蛋白名称 | Triggering receptor expressed on myeloid cells 2 |
| Uniprot ID | |
| 研究领域 | Macrophage / Inflamm. |
| 功能 | May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. |
| 分子量 | Theoretical: 25 kDa. Actual: 35-40 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |