购物车
全部删除 
您的购物车当前为空
Anti-ABCB1 Polyclonal Antibody
一键复制产品信息
还可以货号 TMAB-00021
别名 Phospholipid transporter ABCB1, PGY1, P-glycoprotein 1, Multidrug resistance protein 1, MDR1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, ABCB1
Anti-ABCB1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ABCB1。Anti-ABCB1 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
Anti-ABCB1 Polyclonal Antibody
Anti-ABCB1 Polyclonal Antibody
一键复制产品信息 还可以货号 TMAB-00021 别名 Phospholipid transporter ABCB1, PGY1, P-glycoprotein 1, Multidrug resistance protein 1, MDR1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, ABCB1
Anti-ABCB1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ABCB1。Anti-ABCB1 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
Anti-ABCB1 Polyclonal Antibody 相关产品
资源下载
产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-ABCB1 Polyclonal Antibody is a Rabbit antibody targeting ABCB1. Anti-ABCB1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| 别名 | Phospholipid transporter ABCB1, PGY1, P-glycoprotein 1, Multidrug resistance protein 1, MDR1, CD243, ATP-dependent translocase ABCB1, ATP-binding cassette sub-family B member 1, ABCB1 |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat |
| 验证活性 | 1. Paraformaldehyde-fixed, paraffin embedded Rat Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 4. Paraformaldehyde-fixed, paraffin embedded Rat Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 5. Paraformaldehyde-fixed, paraffin embedded Human Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 6. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 7. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining. 8. Paraformaldehyde-fixed, paraffin embedded Mouse Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with MDR1 Polyclonal Antibody, Unconjugated (TMAB-00021) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.         |
| 应用 | IFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in liver, kidney, small intestine and brain. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas. |
| 免疫原 | KLH conjugated synthetic peptide: human MDR1 |
| 抗原种属 | Human |
| 基因名称 | ABCB1 |
| 基因ID | |
| 蛋白名称 | ATP-dependent translocase ABCB1 |
| Uniprot ID | |
| 研究领域 | P glycoproteins,ATPases,Channels,Side Population,Surface Molecules |
| 功能 | Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. Subunit : Interacts with PSMB5. |
| 分子量 | Theoretical: 141 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
引用文献
评论列表
图片预览
Related Tags: buy Anti-ABCB1 Polyclonal Antibody | purchase Anti-ABCB1 Polyclonal Antibody | Anti-ABCB1 Polyclonal Antibody cost | order Anti-ABCB1 Polyclonal Antibody | Anti-ABCB1 Polyclonal Antibody molecular weight
嗨！有任何问题？点我咨询
版权所有©2015-2025 TargetMol Chemicals Inc.保留所有权利.
沪ICP备20019793号-4 | 沪公网安备 31010602006700号
| 沪(静)应急管危经许[2024]203441
评论内容