MPF Protein, Human, Recombinant (hFc)

MPF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 KDa and the accession number is Q13421.

规格	价格/CNY		数量
10 μg	￥ 580	5日内发货
50 μg	￥ 1,410	5日内发货
500 μg	￥ 9,960	5日内发货
1 mg	￥ 14,200	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 580

5日内发货

50 μg

￥ 1,410

5日内发货

500 μg

￥ 9,960

5日内发货

1 mg

￥ 14,200

5日内发货

产品描述	MPF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 KDa and the accession number is Q13421.

种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q13421
别名	SMR, CAK1, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, MPF, mesothelin, Megakaryocyte potentiating factor, soluble MPF mesothelin related protein, MSLN
氨基酸序列	Leu37-Arg286
蛋白构建	Leu37-Arg286
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	55-75 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.

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MPF Protein, Human, Recombinant (hFc)

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