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Anti-KPNA2 Antibody (9N857) 是一种 Rabbit 抗体,靶向 KPNA2。Anti-KPNA2 Antibody (9N857) 可用于 WB,FCM。
Anti-KPNA2 Antibody (9N857) 是一种 Rabbit 抗体,靶向 KPNA2。Anti-KPNA2 Antibody (9N857) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-KPNA2 Antibody (9N857) is a Rabbit antibody targeting KPNA2. Anti-KPNA2 Antibody (9N857) can be used in WB,FCM. |
别名 | SRP1-α, SRP1-Alpha, SRP1, RCH1, RAG Cohort Protein 1, KPNA2, Karyopherin Subunit α-2, Karyopherin Subunit Alpha-2, Importin Subunit α-2, Importin Subunit Alpha-2 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of KPNA2 on different cell lysates using anti-KPNA2 antibody at 1/1,000 dilution. Postive control: Lane 1: Hela, Lane 2: 293T, Lane 3: HepG2, Lane 4: NIH-3T3, Lane 5: PC-12. 2. Flow cytometric analysis of 293T cells with KPNA2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
应用 | |
推荐剂量 | WB: 1:500-2000; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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