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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody

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货号 TMAB-10446

Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Caveolin-2 (Tyr19)。Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody 可用于 WB。

Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody

Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10446

Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-Caveolin-2 (Tyr19)。Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Caveolin-2 (Tyr19). Anti-Phospho-Caveolin-2 (Tyr19) Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Golgi apparatusmembrane; Peripheral membrane protein. Cell membrane; Peripheralmembrane protein. Membrane, caveola; Peripheral membrane protein.Note=Potential hairpin-like structure in the membrane. Membraneprotein of caveolae. Tyr-19-phosphorylated form is enriched atsites of cell-cell contact and is translocated to the nucleus incomplex with MAPK1 in response to insulin (By similarity).Tyr-27-phosphorylated form is located both in the cytoplasm andplasma membrane. CAV1-mediated Ser-23-phosphorylated form locatesto the plasma membrane. Ser-36-phosphorylated form resides inintracellular compartments.
组织特异性Expressed in endothelial cells, smooth musclecells, skeletal myoblasts and fibroblasts.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cellular localization: Nucleus. Cytoplasm. Golgi apparatus membrane. Cell membrane. Membrane > caveola. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: mouse Caveolin2 around the phosphorylation site of Tyr19.
抗原种属
Mouse
基因名称
CAV2
基因ID
12390
蛋白名称
Caveolin-2
Uniprot ID
Q9WVC3
功能
May act as a scaffolding protein within caveolarmembranes. Interacts directly with G-protein alpha subunits and canfunctionally regulate their activity. Acts as an accessory proteinin conjunction with CAV1 in targeting to lipid rafts and drivingcaveolae formation. The Ser-36 phosphorylated form has a role inmodulating mitosis in endothelial cells. Positive regulator ofcellular mitogenesis of the MAPK signaling pathway. Required forthe insulin-stimulated nuclear translocation and activation ofMAPK1 and STAT3, and the subsequent regulation of cell cycleprogression (By similarity).
化学信息
分子量Theoretical: 18 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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