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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-TPX2 Antibody (5B212)

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货号 TMAB-13710

Anti-TPX2 Antibody (5B212) 是一种 Mouse 抗体，靶向 TPX2。Anti-TPX2 Antibody (5B212) 可用于 WB。

Anti-TPX2 Antibody (5B212)

Anti-TPX2 Antibody (5B212)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13710

Anti-TPX2 Antibody (5B212) 是一种 Mouse 抗体，靶向 TPX2。Anti-TPX2 Antibody (5B212) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-TPX2 Antibody (5B212) is a Mouse antibody targeting TPX2. Anti-TPX2 Antibody (5B212) can be used in WB.
Ig Type
IgG1, k
克隆号
5B212
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules.
组织特异性Expressed in lung carcinoma cell lines but not in normal lung tissues.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景TPX2 is essential for spindle pole and mitotic spindle formulation, playing a role in the S and G2 phases of mitosis. It is also critical for the function of protein kinase Aurora A. TPX2 autophosphorylates Aurora A, targeting it to the spindle apparatus and allowing it to function in eukaryotic meiotic and mitotic cell cycles. TPX2 has also been found to be highly expressed in cancer cells.
抗原信息
免疫原
Recombinant Protein: human TPX2 between 1-531 amino acids
抗原种属
Human
基因名称
TPX2
基因ID
22974
蛋白名称
Targeting protein for Xklp2
Uniprot ID
Q9ULW0
功能
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
化学信息
分子量Theoretical: 86 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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