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IFNAR1 Protein, Mouse, Recombinant (hFc)

产品编号 TMPK-00343

别名: AVP, IFNBR, IFN-alpha/β R1, IFNAR, IFN-aR1, IFN-α-REC, IFNbR1, IFN-R-1, CRF2-1, IFN-alpha-REC, IFN-alpha/beta R1, IFRC, IFN-α/β R1, IFN α/β R1, IFNAR1

IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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IFNAR1 Protein, Mouse, Recombinant (hFc)

规格	价格/CNY		货期	数量
100 μg	￥ 2,960		5日内发货
500 μg	￥ 11,800		5日内发货
1 mg	￥ 19,700		5日内发货

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生物活性

技术参数

产品性质

参考文献

生物活性	Mouse IFN alpha/beta R1, hFc Tag immobilized on CM5 Chip can bind Human IFN alpha 1, hFc Tag with an affinity constant of 20.35 nM as determined in SPR assay.
产品描述	IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.

种属	Mouse
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P33896
别名	AVP, IFNBR, IFN-alpha/β R1, IFNAR, IFN-aR1, IFN-α-REC, IFNbR1, IFN-R-1, CRF2-1, IFN-alpha-REC, IFN-alpha/beta R1, IFRC, IFN-α/β R1, IFN α/β R1, IFNAR1
蛋白构建	Glu27-Thr429
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	72.5 kDa (predicted). Due to glycosylation, the protein migrates to 83-110 kDa based on Tris-Bis PAGE result.

内毒素	< 1 EU/μg by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.

参考文献

1. Teunissen P F A, et al. MAb therapy against the IFN-α/β receptor subunit 1 stimulates arteriogenesis in a murine hindlimb ischaemia model without enhancing atherosclerotic burden[J]. Cardiovascular Research, 2015, 107(2):255-266.

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Keywords

IFNAR1 Protein, Mouse, Recombinant (hFc) AVP IFNBR IFN-alpha/β R1 IFNAR IFN-alpha/b R1 IFN-a-REC IFN-aR1 IFN-α-REC IFNbR1 IFNAR 1 IFN-a/b R1 IFN-R-1 CRF2-1 IFN-alpha-REC IFN-alpha/beta R1 IFNAR-1 IFRC IFN-α/β R1 IFN α/β R1 IFNAR1 recombinant recombinant-proteins proteins protein

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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