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Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) 是一种 Mouse 抗体,靶向 TNFR1/CD120a/TNFRSF1A。Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) 可用于 WB,IP,IF,IHC-P。
Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) 是一种 Mouse 抗体,靶向 TNFR1/CD120a/TNFRSF1A。Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) 可用于 WB,IP,IF,IHC-P。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,990 | 5日内发货 | |
100 μL | ¥ 2,990 | 5日内发货 |
产品描述 | Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) is a Mouse antibody targeting TNFR1/CD120a/TNFRSF1A. Anti-TNFR1/CD120a/TNFRSF1A Antibody (1K754) can be used in WB,IP,IF,IHC-P. |
别名 | tumor necrosis factor receptor superfamily member 1A, TNF-R-I, TNFR60, TNF-R55, TNFR55, TNFR1-d2, TNFR1, TNF-R, TNFAR, TBP1, p60, p55-R, p55, MS5, FPF, CD120a |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of TNF-R1 expression in MCF7 (A), HeLa (B) and U-937 (C) whole cell lysates. 2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic staining of glandular cells. |
应用 | |
推荐剂量 | WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Immunogen affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors. These receptors, designated TNF-R1 and TNF-R2 are expressed on most cell types. The majority of TNF functions are primarily mediated through TNF-R1, while signaling through TNF-R2 occurs less extensively and is confined to cells of the immune system. Both of these proteins belong to the growing TNF and nerve growth factor (NGF) receptor superfamily, which includes FAS, CD30, CD27 and CD40. The members of this superfamily are type I membrane proteins that share sequence homology confined to the extracellular region. TNF-R1 shares a motif coined the “death domain” with FAS and three structurally unrelated signaling proteins, TRADD, FADD and RIP. This “death domain” is required for transduction of the apoptotic signal. |
偶联 | Unconjugated |
免疫原 | Amino acids 30-301 mapping within the extracellular domain of TNF-R1 of human origin |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 55 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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