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Anti-FABP4 Antibody (3V644)
还可以产品编号 TMAY-02238
Anti-FABP4 Antibody (3V644) 是一种 Rabbit 抗体，靶向 FABP4。Anti-FABP4 Antibody (3V644) 可用于 IHC-P,FCM。
Anti-FABP4 Antibody (3V644)
Anti-FABP4 Antibody (3V644)
还可以产品编号 TMAY-02238
Anti-FABP4 Antibody (3V644) 是一种 Rabbit 抗体，靶向 FABP4。Anti-FABP4 Antibody (3V644) 可用于 IHC-P,FCM。
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抗原信息
| 产品描述 | Anti-FABP4 Antibody (3V644) is a Rabbit antibody targeting FABP4. Anti-FABP4 Antibody (3V644) can be used in IHC-P,FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3V644 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human FABP4 in human lung cancer with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human FABP4 in human appendix with rabbit monoclonal antibody (1:2000, formalin-fixed paraffin embedded sections). 3. Flow cytometric analysis of Human FABP4 expression on Hela cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human FABP4, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | IHC-P,FCM |
| 推荐剂量 | IHC-P: 1:1000-1:4000; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human FABP4 / ALBP / A-FABP (rh FABP4 / ALBP / A-FABP; TMPY-02103; P15090; Cys2-Ala132,29Ala/Thr). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FABP4 / ALBP / A-FABP protein (TMPY-02103) |
| 抗原种属 | Human |
| 研究领域 | Early Mesodermal Lineage Markers |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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