Isoniazid-KLH is an antigen-adjuvant conjugate of Isoniazid with keyhole limpet hemocyanin (KLH). This conjugation of the antigen with the protein adjuvant boosts the production of antigen-specific antibodies in vaccine models. The conjugate does not affect protein folding or disrupt primary epitopes, and it enhances cross-presentation and the generation of antigen-specific T cells.