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Anti-IL-13RA2 Antibody-APC (9B615)
还可以产品编号 TMAY-00669A
Anti-IL-13RA2 Antibody-APC (9B615) 是一种 APC-conjugated Rabbit 抗体，靶向 IL-13RA2。Anti-IL-13RA2 Antibody-APC (9B615) 可用于 FCM。
Anti-IL-13RA2 Antibody-APC (9B615)
Anti-IL-13RA2 Antibody-APC (9B615)
还可以产品编号 TMAY-00669A
Anti-IL-13RA2 Antibody-APC (9B615) 是一种 APC-conjugated Rabbit 抗体，靶向 IL-13RA2。Anti-IL-13RA2 Antibody-APC (9B615) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-13RA2 Antibody-APC (9B615) is a APC-conjugated Rabbit antibody targeting IL-13RA2. Anti-IL-13RA2 Antibody-APC (9B615) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9B615 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human IL13Ra2（CD213a2） expression on A375 cells. Cells were stained with APC-conjugated anti-Human IL13Ra2（CD213a2）. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL13RA2 / CD213A2 (rh IL13RA2 / CD213A2; TMPY-00841; NP_000631.1; Met1-Leu342) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High-Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human IL13RA2 / CD213A2 Protein (TMPY-00841) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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