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Anti-DDR1 Antibody-Biotin (1U273)
还可以产品编号 TMAY-01111B
Anti-DDR1 Antibody-Biotin (1U273) 是一种 Biotin-conjugated Rabbit 抗体，靶向 DDR1。Anti-DDR1 Antibody-Biotin (1U273) 可用于 ELISA。
Anti-DDR1 Antibody-Biotin (1U273)
Anti-DDR1 Antibody-Biotin (1U273)
还可以产品编号 TMAY-01111B
Anti-DDR1 Antibody-Biotin (1U273) 是一种 Biotin-conjugated Rabbit 抗体，靶向 DDR1。Anti-DDR1 Antibody-Biotin (1U273) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DDR1 Antibody-Biotin (1U273) is a Biotin-conjugated Rabbit antibody targeting DDR1. Anti-DDR1 Antibody-Biotin (1U273) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1U273 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human DDR1/MCK10/CD167 (rh DDR1/MCK10/CD167; TMPY-01289; NP_001945.3; Met1-Thr416) and then biotinylated. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracellular domain homologous to Dictyostellium discoideum protein discoidin 1. Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. Expression of DDR1/MCK10/CD167 is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. DDR1/MCK10/CD167 plays an important role in regulating attachment to collagen, chemotaxis, proliferation, and MMP production in smooth muscle cells. DDR1 functions in a feedforward loop to increase p53 levels and at least some of its effectors. Inhibition of DDR1 function resulted in strikingly increased apoptosis of wild-type p53-containing cells in response to genotoxic stress through a caspase-dependent pathway. |
| 偶联 | Biotin |
| 其他可选修饰符 | Unconjugated/HRP |
| 可提供抗体种类 | 3 |
| 免疫原 | Recombinant Human DDR1/MCK10/CD167 Protein (TMPY-01289) |
| 抗原种属 | Human |
| 研究领域 | Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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