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Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2

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产品编号 TMAB-10856

Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-IL-1R1 (Tyr496)。Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2 可用于 WB,FCM。

Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2

Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2

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Rating icon 还可以
产品编号 TMAB-10856

Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-IL-1R1 (Tyr496)。Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-IL-1R1 (Tyr496). Anti-Phospho-IL-1R1 (Tyr496) Polyclonal Antibody 2 can be used in WB,FCM.
Ig Type
IgG
交叉反应
Human,Mouse (predicted:Rat,Dog,Pig,Horse)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type I membrane protein. Cell membrane (Probable). Secreted.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II(IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human IL-1R1 around the phosphorylation site of Tyr496
抗原种属
Human
基因名称
IL1R1
基因ID
3554
蛋白名称
Interleukin-1 receptor type 1
Uniprot ID
P14778
功能
Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
化学信息
分子量Theoretical: 63 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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