购物车
- 全部删除
您的购物车当前为空
Anti-LY6E Antibody (6P153)
还可以产品编号 TMAH-00712
Anti-LY6E Antibody (6P153) 是一种抗体，靶向 LY6E。Anti-LY6E Antibody (6P153) 可用于 ELISA, IF。
Anti-LY6E Antibody (6P153)
Anti-LY6E Antibody (6P153)
还可以产品编号 TMAH-00712
Anti-LY6E Antibody (6P153) 是一种抗体，靶向 LY6E。Anti-LY6E Antibody (6P153) 可用于 ELISA, IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LY6E Antibody (6P153) is an antibody targeting LY6E. Anti-LY6E Antibody (6P153) can be used in ELISA, IF. |
| Ig Type | mIgG2a |
| 克隆号 | 6P153 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunofluorescence staining of A549 cell with TMAH-00712 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Mouse IgG(H+L). 2. The Binding Activity of Human LY6E with Anti-LY6E recombinant antibody Activity: Measured by its binding ability in a functional ELISA. Immobilized Human LY6E protein at 2 μg/mL can bind Anti-LY6E recombinant antibody. The EC50 is 2.483-3.282 ng/mL. |
| 应用 | ELISA, IF |
| 推荐剂量 | IF:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| 研究背景 | GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of human coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2, by interfering with spike protein-mediated membrane fusion. Plays also an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta. May also act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. (Microbial infection) Promotes entry, likely through an enhanced virus-cell fusion process, of various viruses including HIV-1, West Nile virus, dengue virus and Zika virus. In contrast, the paramyxovirus PIV5, which enters at the plasma membrane, does not require LY6E. Mechanistically, adopts a microtubule-like organization upon viral infection and enhances viral uncoating after endosomal escape. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human LY6E Protein |
| 抗原种属 | Human |
| 基因ID | 4061 |
| Uniprot ID | |
| 研究领域 | Cell biology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
关键词
评论列表
预览
Related Tags: buy Anti-LY6E Antibody (6P153) | purchase Anti-LY6E Antibody (6P153) | Anti-LY6E Antibody (6P153) cost | order Anti-LY6E Antibody (6P153)
嗨！有任何问题？点我咨询
评论内容