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Anti-CHRNA7 Antibody (5X667) 是一种 Mouse 抗体,靶向 CHRNA7。Anti-CHRNA7 Antibody (5X667) 可用于 WB,IHC,FCM。
Anti-CHRNA7 Antibody (5X667) 是一种 Mouse 抗体,靶向 CHRNA7。Anti-CHRNA7 Antibody (5X667) 可用于 WB,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,990 | 5日内发货 | |
100 μL | ¥ 2,990 | 5日内发货 |
产品描述 | Anti-CHRNA7 Antibody (5X667) is a Mouse antibody targeting CHRNA7. Anti-CHRNA7 Antibody (5X667) can be used in WB,IHC,FCM. |
别名 | Neuronal acetylcholine receptor subunit alpha-7, neuronal acetylcholine receptor protein, alpha-7 chain, NACHRA7, CHRNA7-2, CHRNA 7, cholinergic receptor, nicotinic, alpha polypeptide 7, cholinergic receptor, nicotinic, alpha 7 (neuronal), cholinergic receptor, nicotinic, alpha 7, cholinergic receptor, neuronal nicotinic, alpha polypeptide 7, alpha-7 nicotinic cholinergic receptor subunit, alpha7, alpha 7 neuronal nicotinic acetylcholine receptor, Acra7, AChR, ACHA7_HUMAN, acetylcholine receptor, neuronal nicotinic, alpha-7 subunit, a7 nicotinic acetylcholine receptor, 7nAChR |
克隆号 | 5X667 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of CHRNA7 on human CHRNA7 recombinant protein using anti-CHRNA7 antibody at 1/1,000 dilution. 2. Western blot analysis of CHRNA7 on HEK293 (1) and CHRNA7-hIgGFc transfected HEK293 (2) cell lysate using anti-CHRNA7 antibody at 1/1,000 dilution. 3. Immunohistochemical analysis of paraffin-embedded human bladder cancer tissue using anti-CHRNA7 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human rectum cancer tissue using anti-CHRNA7 antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of SH-SY5Y cells with CHRNA7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα7, also known as NACHRA7, CHRNA7-2 or CHRNA7, is a 502 amino acid multi-pass membrane protein existing as a homopentamer and interacts with RIC-3, a nicotinic acetylcholine receptor (nAChR)-associated protein. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 56 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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