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Anti-Caspase-7 p20 Polyclonal Antibody

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货号 TMAB-03668

Anti-Caspase-7 p20 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Caspase-7 p20。Anti-Caspase-7 p20 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Caspase-7 p20 Polyclonal Antibody

Anti-Caspase-7 p20 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03668

Anti-Caspase-7 p20 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Caspase-7 p20。Anti-Caspase-7 p20 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Caspase-7 p20 Polyclonal Antibody is a Rabbit antibody targeting Caspase-7 p20. Anti-Caspase-7 p20 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Pig,Cow,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human caspase-7 isoform alpha subunit p20
抗原种属
Human
基因名称
CASP7
基因ID
840
蛋白名称
Caspase-7
Uniprot ID
P55210
功能
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
化学信息
分子量Theoretical: 20/33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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