购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IL-4R Polyclonal Antibody 5

一键复制产品信息
Rating icon 还可以
货号 TMAB-07668

Anti-IL-4R Polyclonal Antibody 5 是一种 Rabbit 抗体，靶向 IL-4R。Anti-IL-4R Polyclonal Antibody 5 可用于 WB。

Anti-IL-4R Polyclonal Antibody 5

Anti-IL-4R Polyclonal Antibody 5

一键复制产品信息
Rating icon 还可以
货号 TMAB-07668

Anti-IL-4R Polyclonal Antibody 5 是一种 Rabbit 抗体，靶向 IL-4R。Anti-IL-4R Polyclonal Antibody 5 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,785
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-IL-4R Polyclonal Antibody 5 is a Rabbit antibody targeting IL-4R. Anti-IL-4R Polyclonal Antibody 5 can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.
组织特异性Isoform 1 and isoform 2 are highly expressed in activated T-cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: rat IL-4R
抗原种属
Rat
基因名称
IL4R
基因ID
25084
蛋白名称
Interleukin-4 receptor subunit alpha
Uniprot ID
Q63257
功能
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-IL-4R Polyclonal Antibody 5 | purchase Anti-IL-4R Polyclonal Antibody 5 | Anti-IL-4R Polyclonal Antibody 5 cost | order Anti-IL-4R Polyclonal Antibody 5 | Anti-IL-4R Polyclonal Antibody 5 molecular weight