Anti-IRF6 Antibody (5N5)

Name: Anti-IRF6 Antibody (5N5)
Brand: TargetMol
SKU: TMAY-00115
Rating: 4.5 (1 reviews)

还可以

产品编号 TMAY-00115

Anti-IRF6 Antibody (5N5) 是一种 Mouse 抗体，靶向 IRF6。Anti-IRF6 Antibody (5N5) 可用于 ICC/IF。

Anti-IRF6 Antibody (5N5)

还可以

产品编号 TMAY-00115

Anti-IRF6 Antibody (5N5) 是一种 Mouse 抗体，靶向 IRF6。Anti-IRF6 Antibody (5N5) 可用于 ICC/IF。

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生物活性

产品描述	Anti-IRF6 Antibody (5N5) is a Mouse antibody targeting IRF6. Anti-IRF6 Antibody (5N5) can be used in ICC/IF.
Ig Type	Monoclonal Mouse IgG3
克隆号	5N5
交叉反应	Human
验证活性	Immunofluorescence staining of Human IRF6 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with mouse anti-Human IRF6 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody(green). Positive staining was localized to cytoplasm and nucleus.
应用	ICC/IF
推荐剂量	ICC-IF: 1:20-1:100
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the human IRF6. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	IRF6 (Interferon Regulatory Factor 6) is a Protein Coding gene. IRF6, a member of the IRF family of transcription factors, is required for the differentiation of skin, breast epithelium, and oral epithelium. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. IRF6, the gene that causes van der Woude syndrome (VWS), is a candidate gene for nonsyndromic cleft lip with or without cleft palate (NSCLP) because some studies have supported an association between NSCLP and single nucleotide polymorphisms (SNPs) in IRF6 in several populations. Interferon Regulatory Factor 6 (IRF6) gene variants are significant genetic contributors to orofacial clefts.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	A synthetic peptide corresponding to the C-terminus of the human IRF6
抗原种属	Human
研究领域	Apoptosis Transcription Factors and Regulators

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.