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Anti-CEACAM6 Antibody-PE (1L889)
还可以产品编号 TMAY-01222P
Anti-CEACAM6 Antibody-PE (1L889) 是一种 PE-conjugated Rabbit 抗体，靶向 CEACAM6。Anti-CEACAM6 Antibody-PE (1L889) 可用于 FCM。
Anti-CEACAM6 Antibody-PE (1L889)
Anti-CEACAM6 Antibody-PE (1L889)
还可以产品编号 TMAY-01222P
Anti-CEACAM6 Antibody-PE (1L889) 是一种 PE-conjugated Rabbit 抗体，靶向 CEACAM6。Anti-CEACAM6 Antibody-PE (1L889) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CEACAM6 Antibody-PE (1L889) is a PE-conjugated Rabbit antibody targeting CEACAM6. Anti-CEACAM6 Antibody-PE (1L889) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1L889 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of human CEACAM6 expression on human whole blood granulocytes. Human whole blood granulocytes were stained with PE-conjugated anti-Human CEACAM6. The histogram were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM6 / CD66c (rh CEACAM6 / CD66c; 10823-H08H; Met 1-Gly 320; NP_002474.4) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/PerCP/FITC/HRP |
| 可提供抗体种类 | 6 |
| 免疫原 | Human cell-derived rhCEACAM6 (TMPY-00971) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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