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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GHRHR Polyclonal Antibody

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货号 TMAB-06471

Anti-GHRHR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GHRHR。Anti-GHRHR Polyclonal Antibody 可用于 WB。

Anti-GHRHR Polyclonal Antibody

Anti-GHRHR Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06471

Anti-GHRHR Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GHRHR。Anti-GHRHR Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-GHRHR Polyclonal Antibody is a Rabbit antibody targeting GHRHR. Anti-GHRHR Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Horse)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
组织特异性Pituitary gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary. GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH. Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation. In addition, this signalling pathway may have direct action in fetal/placental development, reproduction and immune function. GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS). The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1. Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH).
抗原信息
免疫原
KLH conjugated synthetic peptide: human GHRHR
抗原种属
Human
基因名称
GHRHR
基因ID
2692
蛋白名称
Growth hormone-releasing hormone receptor
Uniprot ID
Q02643
功能
Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion.
化学信息
分子量Theoretical: 45 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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