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Anti-COMP Antibody (8Z374)
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产品编号 TMAY-00401
别名 THBS5, PSACH, MED, EPD1, EDM1, cartilage oligomeric matrix protein
Anti-COMP Antibody (8Z374) 是一种 Mouse 抗体，靶向 COMP。Anti-COMP Antibody (8Z374) 可用于 ELISA(Cap)。
Anti-COMP Antibody (8Z374)
331 Anti-COMP Antibody (8Z374)
还可以产品编号 TMAY-00401 别名 THBS5, PSACH, MED, EPD1, EDM1, cartilage oligomeric matrix protein
Anti-COMP Antibody (8Z374) 是一种 Mouse 抗体，靶向 COMP。Anti-COMP Antibody (8Z374) 可用于 ELISA(Cap)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 585 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-COMP Antibody (8Z374) is a Mouse antibody targeting COMP. Anti-COMP Antibody (8Z374) can be used in ELISA(Cap). |
| 别名 | THBS5, PSACH, MED, EPD1, EDM1, cartilage oligomeric matrix protein |
| Ig Type | Mouse IgG1 |
| 克隆号 | 8Z374 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human COMP (rh COMP; TMPY-00725; NP_000086.2; Met1-Ala757). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Cartilage Oligomeric Matrix Protein (COMP), also referred to as Thrombospondin-5, is a non-collagenous extracellular matrix (ECM) protein and belongs to the subgroup B of the thrombospondin protein family. This protein is expressed primarily in cartilage, ligament, and tendon, and binds to other ECM proteins such as collagen I, II and IX with high affinities depending on the divalent cations Zn2+ or Ni2+. COMP is a secreted glycoprotein that is important for growth plate organization and function. It is suggested to play a role in cell growth and development, and recent studies have revealed the possible mechanism that it protects cells against death by elevating members of the IAP (inhibitor of apoptosis protein) family of survival proteins. Mutations in COMP cause two skeletal dysplasias, pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (EDM1), and up-regulated expression of COMP are observed in rheumatoid arthritis and certain carcinomas. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human COMP Protein (TMPY-00725) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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