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Anti-TYROBP Polyclonal Antibody

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产品编号 TMAB-01922
别名 TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12

Anti-TYROBP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TYROBP。Anti-TYROBP Polyclonal Antibody 可用于 FCM。

Anti-TYROBP Polyclonal Antibody

Anti-TYROBP Polyclonal Antibody

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产品编号 TMAB-01922 别名 TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12

Anti-TYROBP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 TYROBP。Anti-TYROBP Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-TYROBP Polyclonal Antibody is a Rabbit antibody targeting TYROBP. Anti-TYROBP Polyclonal Antibody can be used in FCM.
别名TYRO protein tyrosine kinase binding protein, TYOBP, PLOSL, Killer-activating receptor-associated protein, KAR-associated protein, KARAP, DNAX-activation protein 12, DAP12, DAP 12
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep)
验证活性
Blank control: mouse splenocytes (blue)
Isotype Control Antibody: Rabbit IgG-Pe (orange);
Primary Antibody Dilution: 1 μL in 100 μL 1X PBS containing 0.5% BSA (green).
verifiedActivity
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen. Also found in b
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human DAP12
抗原种属
Human
基因名称
TYROBP
基因ID
7305
蛋白名称
TYRO protein tyrosine kinase-binding protein
Uniprot ID
O43914
研究领域
Transmembrane
功能
Non-covalently associates with activating receptors of the CD300 family. Cross-linking of CD300-TYROBP complexes results in cellular activation. Involved for instance in neutrophil activation mediated by integrin.
化学信息
分子量Theoretical: 10 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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