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Anti-C-Myc Polyclonal Antibody 2

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货号 TMAB-04484

Anti-C-Myc Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 C-Myc。Anti-C-Myc Polyclonal Antibody 2 可用于 WB。

Anti-C-Myc Polyclonal Antibody 2

Anti-C-Myc Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04484

Anti-C-Myc Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 C-Myc。Anti-C-Myc Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-C-Myc Polyclonal Antibody 2 is a Rabbit antibody targeting C-Myc. Anti-C-Myc Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus, nucleoplasm.
组织特异性Low levels detected throughout embryo before cellular blastoderm formation, particularly concentrated in pole plasm. Zygotic expression detected during cellular blastoderm stage in endodermal anlagen of anterior and posterior midgut at both poles. After gastrulation, expression detected in invaginating ventral furrow of mesoderm. Continued expression in anterior and posterior midgut and mesoderm during germband extension. During late germ-band retraction, expression remains detectable in fusing midgut and presumed developing somatic musculature.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human C-Myc
抗原种属
Human
基因名称
MYC
基因ID
蛋白名称
Myc proto-oncogene protein
Uniprot ID
功能
Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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